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Orientation of palmitoylated Ca(V)β2a relative to Ca(V)2.2 is critical for slow pathway modulation of N-type Ca(2+) current by tachykinin receptor activation

The G(q)-coupled tachykinin receptor (neurokinin-1 receptor [NK-1R]) modulates N-type Ca(2+) channel (Ca(V)2.2 or N channel) activity at two distinct sites by a pathway involving a lipid metabolite, most likely arachidonic acid (AA). In another study published in this issue (Heneghan et al. 2009. J....

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Detalhes bibliográficos
Main Authors: Mitra-Ganguli, Tora, Vitko, Iuliia, Perez-Reyes, Edward, Rittenhouse, Ann R.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768804/
https://ncbi.nlm.nih.gov/pubmed/19858358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200910204
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