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Orientation of the Calcium Channel β Relative to the α(1)2.2 Subunit Is Critical for Its Regulation of Channel Activity
BACKGROUND: The Ca(v)β subunits of high voltage-activated Ca(2+) channels control the trafficking and biophysical properties of the α(1) subunit. The Ca(v)β-α(1) interaction site has been mapped by crystallographic studies. Nevertheless, how this interaction leads to channel regulation has not been...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2570331/ https://ncbi.nlm.nih.gov/pubmed/18958281 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003560 |
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