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A Continuum of Cell States Spans Pluripotency and Lineage Commitment in Human Embryonic Stem Cells
BACKGROUND: Commitment in embryonic stem cells is often depicted as a binary choice between alternate cell states, pluripotency and specification to a particular germ layer or extraembryonic lineage. However, close examination of human ES cell cultures has revealed significant heterogeneity in the s...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2768791/ https://ncbi.nlm.nih.gov/pubmed/19890402 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007708 |
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