HIPK2 modulates p53 activity towards pro-apoptotic transcription

BACKGROUND: Activation of p53-mediated gene transcription is a critical cellular response to DNA damage and involves a phosphorylation-acetylation cascade of p53. The discovery of differences in the response to different agents raises the question whether some of the p53 oncosuppressor functions mig...

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Main Authors: Puca, Rosa, Nardinocchi, Lavinia, Sacchi, Ada, Rechavi, Gideon, Givol, David, D'Orazi, Gabriella
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2009
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768676/
https://ncbi.nlm.nih.gov/pubmed/19828042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-8-85
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