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Two mammalian MOF complexes regulate transcription activation by distinct mechanisms
In mammals, MYST family histone acetyltransferase MOF plays important roles in transcription activation by acetylating histone H4 on K16, a prevalent mark associated with chromatin decondensation, and transcription factor p53 on K120, which is important for activation of pro-apoptotic genes. However...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2768600/ https://ncbi.nlm.nih.gov/pubmed/19854137 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.07.031 |
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