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Two mammalian MOF complexes regulate transcription activation by distinct mechanisms

In mammals, MYST family histone acetyltransferase MOF plays important roles in transcription activation by acetylating histone H4 on K16, a prevalent mark associated with chromatin decondensation, and transcription factor p53 on K120, which is important for activation of pro-apoptotic genes. However...

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Detalhes bibliográficos
Main Authors: Li, Xiangzhi, Wu, Lipeng, Corsa, Callie Ann Sprunger, Kunkel, Steve, Dou, Yali
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768600/
https://ncbi.nlm.nih.gov/pubmed/19854137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.07.031
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