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Inhibition of Osteoblast Functions by IKK/NF-κB in Osteoporosis

An imbalance in bone formation relative to bone resorption results in the net bone loss in osteoporosis and inflammatory bone diseases. While it is well known how bone resorption is stimulated, the molecular mechanisms that mediate impaired bone formation are poorly understood. Here we show that the...

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Autors principals: Chang, Jia, Wang, Zhuo, Tang, Eric, Fan, Zhipeng, McCauley, Laurie, Franceschi, Renny, Guan, Kunliang, Krebsbach, Paul H., Wang, Cun-Yu
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768554/
https://ncbi.nlm.nih.gov/pubmed/19448637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.1954
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