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Inhibition of Osteoblast Functions by IKK/NF-κB in Osteoporosis

An imbalance in bone formation relative to bone resorption results in the net bone loss in osteoporosis and inflammatory bone diseases. While it is well known how bone resorption is stimulated, the molecular mechanisms that mediate impaired bone formation are poorly understood. Here we show that the...

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Detalhes bibliográficos
Main Authors: Chang, Jia, Wang, Zhuo, Tang, Eric, Fan, Zhipeng, McCauley, Laurie, Franceschi, Renny, Guan, Kunliang, Krebsbach, Paul H., Wang, Cun-Yu
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768554/
https://ncbi.nlm.nih.gov/pubmed/19448637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.1954
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