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The Cochaperone BAG2 Sweeps Paired Helical Filament- Insoluble Tau from the Microtubule
Tau inclusions are a prominent feature of many neurodegenerative diseases including Alzheimer's disease. Their accumulation in neurons as ubiquitinated filaments suggests a failure in the degradation limb of the Tau pathway. The components of a Tau protein triage system consisting of CHIP/Hsp70...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Society for Neuroscience
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2768429/ https://ncbi.nlm.nih.gov/pubmed/19228967 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4660-08.2009 |
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