The Parkinson Disease Protein Leucine-Rich Repeat Kinase 2 Transduces Death Signals via Fas-Associated Protein with Death Domain and Caspase-8 in a Cellular Model of Neurodegeneration

Neurodegenerative illnesses such as Parkinson and Alzheimer disease are an increasingly prevalent problem in aging societies, yet no therapies exist that retard or prevent neurodegeneration. Dominant missense mutations in leucine-rich repeat kinase 2 (LRRK2) are the most common genetic cause of Park...

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Hlavní autoři: Ho, Cherry Cheng-Ying, Rideout, Hardy J., Ribe, Elena, Troy, Carol M., Dauer, William T.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2009
Témata:
Brief Communications
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768412/
https://ncbi.nlm.nih.gov/pubmed/19176810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5175-08.2009
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