The Parkinson Disease Protein Leucine-Rich Repeat Kinase 2 Transduces Death Signals via Fas-Associated Protein with Death Domain and Caspase-8 in a Cellular Model of Neurodegeneration

Neurodegenerative illnesses such as Parkinson and Alzheimer disease are an increasingly prevalent problem in aging societies, yet no therapies exist that retard or prevent neurodegeneration. Dominant missense mutations in leucine-rich repeat kinase 2 (LRRK2) are the most common genetic cause of Park...

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Bibliografske podrobnosti
Main Authors: Ho, Cherry Cheng-Ying, Rideout, Hardy J., Ribe, Elena, Troy, Carol M., Dauer, William T.
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2009
Teme:
Brief Communications
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768412/
https://ncbi.nlm.nih.gov/pubmed/19176810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5175-08.2009
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