Hyperoxia causes angiopoietin 2–mediated acute lung injury and necrotic cell death

The angiogenic growth factor angiopoietin 2 (Ang2) destabilizes blood vessels, enhances vascular leak and induces vascular regression and endothelial cell apoptosis. We considered that Ang2 might be important in hyperoxic acute lung injury (ALI). Here we have characterized the responses in lungs ind...

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Autori principali: Bhandari, Vineet, Choo-Wing, Rayman, Lee, Chun G, Zhu, Zhou, Nedrelow, Jonathan H, Chupp, Geoffrey L, Zhang, Xucher, Matthay, Michael A, Ware, Lorraine B, Homer, Robert J, Lee, Patty J, Geick, Anke, de Fougerolles, Antonin R, Elias, Jack A
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2006
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768268/
https://ncbi.nlm.nih.gov/pubmed/17086189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm1494
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