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Caveolin-1 and Altered Neuregulin Signaling Contribute to the Pathophysiological Progression of Diabetic Peripheral Neuropathy

OBJECTIVE: Evaluate if Erb B2 activation and the loss of caveolin-1 (Cav1) contribute to the pathophysiological progression of diabetic peripheral neuropathy (DPN). RESEARCH DESIGN AND METHODS: Cav1 knockout and wild-type C57BL/6 mice were rendered diabetic with streptozotocin, and changes in motor...

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Autors principals: McGuire, James F., Rouen, Shefali, Siegfreid, Eric, Wright, Douglas E., Dobrowsky, Rick T.
Format: Artigo
Idioma:Inglês
Publicat: American Diabetes Association 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768162/
https://ncbi.nlm.nih.gov/pubmed/19675140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-0594
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