Irinotecan-induced mucositis manifesting as diarrhoea corresponds with an amended intestinal flora and mucin profile

Chemotherapy-induced diarrhoea is a major oncological problem, caused by the cytotoxic effects of cancer chemotherapy. Irinotecan is linked with severe mucositis and diarrhoea, the mechanisms of which remain poorly understood. Bacterial β-glucuronidase is thought to be involved in the metabolism of...

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Detalhes bibliográficos
Main Authors: Stringer, Andrea M, Gibson, Rachel J, Bowen, Joanne M, Logan, Richard M, Ashton, Kimberly, Yeoh, Ann SJ, Al-Dasooqi, Noor, Keefe, Dorothy MK
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2009
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768147/
https://ncbi.nlm.nih.gov/pubmed/19765103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2613.2009.00671.x
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