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The PAR-6 Polarity Protein Controls Dendritic Spine Density Through p190 RhoGAP and the Rho GTPase
The majority of excitatory synaptic transmission in the brain occurs at dendritic spines, which are actin-rich protrusions on the dendrites. The polarized nature of these structures suggests that proteins regulating cell polarity might be involved in their formation. Indeed, the polarity protein PAR...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2768076/ https://ncbi.nlm.nih.gov/pubmed/18267090 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2007.11.020 |
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