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The PAR-6 Polarity Protein Controls Dendritic Spine Density Through p190 RhoGAP and the Rho GTPase

The majority of excitatory synaptic transmission in the brain occurs at dendritic spines, which are actin-rich protrusions on the dendrites. The polarized nature of these structures suggests that proteins regulating cell polarity might be involved in their formation. Indeed, the polarity protein PAR...

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Bibliographic Details
Main Authors: Zhang, Huaye, Macara, Ian G.
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768076/
https://ncbi.nlm.nih.gov/pubmed/18267090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2007.11.020
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