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The c-Cbl proto-oncoprotein downregulates EBV LMP2A signaling
Latent membrane protein 2A (LMP2A) of Epstein-Barr virus (EBV) plays a key role in regulating viral latency and EBV pathogenesis by functionally mimicking signals induced by the B-cell receptor (BCR) altering normal B cell development. As c-Cbl ubiquitin ligase (E3) is a critical negative regulator...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2768052/ https://ncbi.nlm.nih.gov/pubmed/19081591 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2008.11.018 |
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