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Crystal structures of Lys-63-linked tri- and di-ubiquitin reveal a highly extended chain architecture
The covalent attachment of different types of poly-ubiquitin chains signal different outcomes for the proteins so targeted. For example, a protein modified with Lys-48-linked poly-ubiquitin chains is targeted for proteasomal degradation, whereas Lys-63-linked chains encode non-degradative signals. T...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2767448/ https://ncbi.nlm.nih.gov/pubmed/19731378 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22568 |
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