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Cytokine Treatment of Macrophage Suppression of T Cell Activation

High Mφ:T cell ratios suppress the immune response to the retroviral superantigen Mls by IFNγ-triggered production of the arg- and trp-consuming enzymes iNOS and IDO. Attempts to reverse suppression by treatment with pro-inflammatory cytokines revealed that IL-6 improved the T cell response to Mls a...

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Bibliografiske detaljer
Main Authors: Silberman, Daniel, Bucknum, Amanda, Kozlowski, Megan, Matlack, Robin, Riggs, James
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2767421/
https://ncbi.nlm.nih.gov/pubmed/19249120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imbio.2009.01.015
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