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Pathogenic RNAs in Microsatellite Expansion Disease

The expansion of unstable microsatellites is the cause of a number of inherited neuromuscular and neurological disorders. While these expanded repeats can be located in either the coding or non-coding regions of genes, toxic RNA transcripts have been primarily implicated in the pathogenesis of non-c...

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Autors principals: Shin, Jihae, Charizanis, Konstantinos, Swanson, Maurice S.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2767409/
https://ncbi.nlm.nih.gov/pubmed/19647781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2009.07.079
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