A chemical-genetic approach to study G protein regulation of β cell function in vivo

Impaired functioning of pancreatic β cells is a key hallmark of type 2 diabetes. β cell function is modulated by the actions of different classes of heterotrimeric G proteins. The functional consequences of activating specific β cell G protein signaling pathways in vivo are not well understood at pr...

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Detalhes bibliográficos
Main Authors: Guettier, Jean-Marc, Gautam, Dinesh, Scarselli, Marco, de Azua, Inigo Ruiz, Li, Jian Hua, Rosemond, Erica, Ma, Xiaochao, Gonzalez, Frank J., Armbruster, Blaine N., Lu, Huiyan, Roth, Bryan L., Wess, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2767362/
https://ncbi.nlm.nih.gov/pubmed/19858481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0906593106
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