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In Vitro Acetylcholinesterase Inhibition by Type A Botulinum Toxin
Type A botulinum toxin was studied for its ability to inhibit the action of acetyl-cholinesterase. The chromogenic substrate, indophenyl acetate, was used for assay of enzyme activity. Inhibition of enzyme function was detected through use of both 6.6 × 10(−6) mg (20 ld(50)) and 6.6 × 10(−10) mg (2...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1967
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC276736/ https://ncbi.nlm.nih.gov/pubmed/4860916 |
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