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In Vitro Acetylcholinesterase Inhibition by Type A Botulinum Toxin

Type A botulinum toxin was studied for its ability to inhibit the action of acetyl-cholinesterase. The chromogenic substrate, indophenyl acetate, was used for assay of enzyme activity. Inhibition of enzyme function was detected through use of both 6.6 × 10(−6) mg (20 ld(50)) and 6.6 × 10(−10) mg (2...

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Bibliografske podrobnosti
Main Authors: Marshall, R., Quinn, L. Y.
Format: Artigo
Jezik:Inglês
Izdano: 1967
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC276736/
https://ncbi.nlm.nih.gov/pubmed/4860916
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