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In Vitro Acetylcholinesterase Inhibition by Type A Botulinum Toxin

Type A botulinum toxin was studied for its ability to inhibit the action of acetyl-cholinesterase. The chromogenic substrate, indophenyl acetate, was used for assay of enzyme activity. Inhibition of enzyme function was detected through use of both 6.6 × 10(−6) mg (20 ld(50)) and 6.6 × 10(−10) mg (2...

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Detalhes bibliográficos
Publicado no:J Bacteriol
Principais autores: Marshall, R., Quinn, L. Y.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1967
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC276736/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4860916/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.94.4.812-814.1967
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