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Calcitriol derivatives with two different side chains at C-20. V. Potent Inhibitors of Mammary Carcinogenesis and Inducers of Leukemia Differentiation

Calcitriol is implicated in many cellular functions including cellular growth and differentiation thus explaining its anti-tumor effects. It was shown that gemini, the calcitriol derivative containing two side chain at C20, is also active in gene transcription with enhanced anti-tumor activity. We h...

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Detalhes bibliográficos
Main Authors: Maehr, Hubert, Lee, Hong Jin, Perry, Bradford, Suh, Nanjoo, Uskokovic, Milan R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2767326/
https://ncbi.nlm.nih.gov/pubmed/19685888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm900780q
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