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Impaired macrophage function following bacterial stimulation in chronic granulomatous disease

Nicotinamide adenine dinucleotide phosphate (NADPH) oxidase is critical for phagocyte anti-microbial activity and plays a major role in innate immunity. Defects in genes coding for components of the NADPH oxidase enzyme system are responsible for chronic granulomatous disease (CGD), a rare primary n...

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Autors principals: Rahman, Farooq Z, Hayee, Bu’Hussain, Chee, Ronnie, Segal, Anthony W, Smith, Andrew M
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2767315/
https://ncbi.nlm.nih.gov/pubmed/19740382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2009.03112.x
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