CHRONIC ACTIONS OF A NOVEL ORAL B-TYPE NATRIURETIC PEPTIDE CONJUGATE IN NORMAL DOGS AND ACUTE ACTIONS IN ANGIOTENSIN II MEDIATED HYPERTENSION

BACKGROUND: We previously reported the feasibility of acute orally delivered newly developed conjugated form of human BNP (hBNP) in normal animals. The objective of the current study was to extend our findings and to define the chronic actions of an advanced oral conjugated hBNP (hBNP-054) administe...

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Detalhes bibliográficos
Main Authors: Cataliotti, Alessandro, Chen, Horng H., Schirger, John A., Martin, Fernando L., Boerrigter, Guido, Costello-Boerrigter, Lisa C., James, Kenneth D., Polowy, Karen, Miller, Mark A., Malkar, Navdeep B., Bailey, Kent R., Burnett, John C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2767302/
https://ncbi.nlm.nih.gov/pubmed/18838565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.107.759241
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