CHRONIC ACTIONS OF A NOVEL ORAL B-TYPE NATRIURETIC PEPTIDE CONJUGATE IN NORMAL DOGS AND ACUTE ACTIONS IN ANGIOTENSIN II MEDIATED HYPERTENSION

BACKGROUND: We previously reported the feasibility of acute orally delivered newly developed conjugated form of human BNP (hBNP) in normal animals. The objective of the current study was to extend our findings and to define the chronic actions of an advanced oral conjugated hBNP (hBNP-054) administe...

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Détails bibliographiques
Auteurs principaux: Cataliotti, Alessandro, Chen, Horng H., Schirger, John A., Martin, Fernando L., Boerrigter, Guido, Costello-Boerrigter, Lisa C., James, Kenneth D., Polowy, Karen, Miller, Mark A., Malkar, Navdeep B., Bailey, Kent R., Burnett, John C.
Format: Artigo
Langue:Inglês
Publié: 2008
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2767302/
https://ncbi.nlm.nih.gov/pubmed/18838565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.107.759241
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