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The functional expression of toxic genes: Lessons learned from molecular cloning of CCH1, a high-affinity Ca(2+) channel

Some genes cannot be cloned by conventional methods because in most cases the genes or gene products are toxic to E. coli. CCH1 is a high-affinity Ca(2+) channel present in the plasma membrane of Cryptococcus neoformans and other fungi. Like many toxic genes, the molecular cloning of CCH1 has been a...

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Hlavní autoři: Vu, Kiem, Bautos, Jennifer, Hong, Min-Pyo, Gelli, Angie
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2767258/
https://ncbi.nlm.nih.gov/pubmed/19580778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2009.06.039
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