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Mechanisms of Toll-Like Receptor 4 (TLR4)-Mediated Inflammation After Cold Ischemia/Reperfusion in the Heart
BACKGROUND: TLR4 signaling mediates early inflammation after cold I/R. We hypothesized that the TLR4 co-receptor CD14, the intracellular adaptor proteins MyD88 and TRIF would be required for cold I/R induced inflammation. HMGB1 is a putative endogenous activator of TLR4. Therefore, we also assessed...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2766805/ https://ncbi.nlm.nih.gov/pubmed/19461481 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0b013e3181a36e5e |
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