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Zinc Inhibits Amyloid β Production from Alzheimer's Amyloid Precursor Protein in SH-SY5Y Cells

Zinc released from excited glutamatergic neurons accelerates amyloid β (Aβ) aggregation, underscoring the therapeutic potential of zinc chelation for the treatment of Alzheimer's disease (AD). Zinc can also alter Aβ concentration by affecting its degradation. In order to elucidate the possible...

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Autors principals: Lee, Jinu, Kim, Chul Hoon, Kim, Dong Goo, Ahn, Young Soo
Format: Artigo
Idioma:Inglês
Publicat: The Korean Physiological Society and The Korean Society of Pharmacology 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2766728/
https://ncbi.nlm.nih.gov/pubmed/19885037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2009.13.3.195
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