Quantitative Structure Activity Relationship between Diazabicyclo[4.2.0]octanes Derivatives and Nicotinic Acetylcholine Receptor Agonists

Three dimensional quantitative structure activity relationship between diazabicyclo[4.2.0]octanes and nicotinic acetylcholine receptor (hα4β2 and hα3β4) agonists was studied using comparative molecular field analysis (CoMFA) and comparative molecular similarity indices analysis (CoMSIA). From 11 CoM...

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Detalhes bibliográficos
Main Authors: Kim, Eun Ae, Jung, Kyoung Chul, Sohn, Uy Dong, Im, Chaeuk
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Physiological Society and The Korean Society of Pharmacology 2009
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2766720/
https://ncbi.nlm.nih.gov/pubmed/19885027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2009.13.1.55
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