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Specific Human Astrocyte Subtype Revealed by Affinity Purified GFAP(+1) Antibody; Unpurified Serum Cross-Reacts with Neurofilament-L in Alzheimer

The human GFAP splice variants GFAPΔ164 and GFAPΔexon6 both result in a GFAP protein isoform with a unique out-of-frame carboxy-terminus that can be detected by the GFAP(+1) antibody. We previously reported that GFAP(+1) was expressed in astrocytes and in degenerating neurons in Alzheimer's dis...

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Main Authors: Middeldorp, Jinte, van den Berge, Simone A., Aronica, Eleonora, Speijer, Dave, Hol, Elly M.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2766629/
https://ncbi.nlm.nih.gov/pubmed/19888461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007663
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