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Regulation of interleukin-12/interleukin-23 production and the T-helper 17 response in humans

Interleukin-12 (IL-12) and IL-23 share a common chain. Yet, their production in response to pathogens is differentially regulated, and their functions are distinct and often antithetic. IL-12 is involved in the induction or amplification of the T-helper type 1 (Th1) response, whereas IL-23 has been...

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Bibliografiske detaljer
Main Authors: Lyakh, Lyudmila, Trinchieri, Giorgio, Provezza, Lisa, Carra, Giuseppe, Gerosa, Franca
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2766610/
https://ncbi.nlm.nih.gov/pubmed/19161420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-065X.2008.00700.x
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