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Targeting Akt3 Signaling in Malignant Melanoma Using Isoselenocyanates

PURPOSE: Melanoma is the most invasive and deadly form of skin cancer. Few agents are available for treating advanced disease to enable long-term patient survival, which is driving the search for new compounds inhibiting deregulated pathways causing melanoma. Akt3 is an important target in melanomas...

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Hlavní autoři: Sharma, Arati, Sharma, Arun K., Madhunapantula, SubbaRao V., Desai, Dhimant, Huh, Sung Jin, Mosca, Paul, Amin, Shantu, Robertson, Gavin P.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2766355/
https://ncbi.nlm.nih.gov/pubmed/19208796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-2214
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