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Statins Block Calcific Nodule Formation of Valvular Interstitial Cells by Inhibiting α-Smooth Muscle Actin Expression
OBJECTIVE: Calcific aortic stenosis, characterized by excessive fibrosis and deposition of bone-like calcified tissue, affects roughly 2–3% of the US population over 65. Recent studies have suggested that statins have a positive effect on the progression of aoritic stenosis, likely due to their abil...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2766347/ https://ncbi.nlm.nih.gov/pubmed/19679827 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.109.195271 |
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