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Replication of genetic associations as pseudoreplication due to shared genealogy

The genotypes of individuals in replicate genetic association studies have some level of correlation due to shared descent in the complete pedigree of all living humans. As a result of this genealogical sharing, replicate studies that search for genotype-phenotype associations using linkage disequil...

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Détails bibliographiques
Auteurs principaux: Rosenberg, Noah A., VanLiere, Jenna M.
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2766236/
https://ncbi.nlm.nih.gov/pubmed/19191270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20400
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