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Mathematical properties of the r(2) measure of linkage disequilibrium
Statistics for linkage disequilibrium (LD), the non-random association of alleles at two loci, depend on the frequencies of the alleles at the loci under consideration. Here, we examine the r(2) measure of LD and its mathematical relationship to allele frequencies, quantifying the constraints on its...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2580747/ https://ncbi.nlm.nih.gov/pubmed/18572214 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tpb.2008.05.006 |
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