Fyn Mediates Leptin Actions in the Thymus of Rodents

BACKGROUND: Several effects of leptin in the immune system rely on its capacity to modulate cytokine expression and apoptosis in the thymus. Surprisingly, some of these effects are dependent on signal transduction through the IRS1/PI3-kinase, but not on the activation of JAK2. Since all the well kno...

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Bibliographic Details
Main Authors: Girasol, Alessandra, Albuquerque, Gabriela G., Mansour, Eli, Araújo, Eliana P., Degasperi, Giovanna, Denis, Raphael G., Carvalheira, José B., Saad, Mário J., Velloso, Lício A.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2009
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2766049/
https://ncbi.nlm.nih.gov/pubmed/19888448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007707
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