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Smooth Muscle LDL Receptor-related Protein-1 Inactivation Reduces Vascular Reactivity and Promotes Injury-induced Neointima Formation

OBJECTIVE: Defective smooth muscle expression of LDL receptor-related protein-1 (Lrp1) increases atherosclerosis in hypercholesterolemic mice. This study explored the importance of smooth muscle Lrp1 expression under normolipidemic conditions. METHODS AND RESULTS: Smooth muscle cells isolated from c...

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Main Authors: Basford, Joshua E., Moore, Zachary W.Q., Zhou, Li, Herz, Joachim, Hui, David Y.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2766037/
https://ncbi.nlm.nih.gov/pubmed/19729608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.109.194357
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