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Genetic ablation of retinal pigment epithelial cells reveals the adaptive response of the epithelium and impact on photoreceptors

The retinal pigment epithelium (RPE) plays a critical role in the maintenance of the outer retina. RPE cell death or dysfunction drives the pathophysiology of many retinal diseases, but the physiological response of the retina to RPE cell loss is poorly understood, mainly because of the absence of s...

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Bibliografiske detaljer
Main Authors: Longbottom, Rebecca, Fruttiger, Marcus, Douglas, Ron H., Martinez-Barbera, Juan Pedro, Greenwood, John, Moss, Stephen E.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765920/
https://ncbi.nlm.nih.gov/pubmed/19850870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0902593106
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