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Crystallization and preliminary X-ray analysis of a d-­Ala:d-Ser ligase associated with VanG-type vancomycin resistance

Acquired VanG-type resistance to vancomycin in Enterococcus faecalis BM4518 arises from inducible synthesis of peptidoglycan precursors ending in d-alanyl-d-serine, to which vancomycin exhibits low binding affinity. VanG, a d-alanine:d-serine ligase, catalyzes the ATP-dependent synthesis of the d-Al...

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書誌詳細
主要な著者: Weber, Patrick, Meziane-Cherif, Djalal, Haouz, Ahmed, Saul, Frederick A., Courvalin, Patrice
フォーマット: Artigo
言語:Inglês
出版事項: International Union of Crystallography 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765892/
https://ncbi.nlm.nih.gov/pubmed/19851013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309109033831
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