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The structure of Staphylococcus aureus phosphopantetheine adenylyltransferase in complex with 3′-phosphoadenosine 5′-phosphosulfate reveals a new ligand-binding mode
Bacterial phosphopantetheine adenylyltransferase (PPAT) catalyzes the penultimate step in the coenzyme A (CoA) biosynthetic pathway. It catalyzes the reversible transfer of an adenylyl group from ATP to 4′-phosphopantetheine (Ppant) to form dephospho-CoA (dPCoA) and pyrophosphate. Previous structur...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
International Union of Crystallography
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2765882/ https://ncbi.nlm.nih.gov/pubmed/19851003 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309109036616 |
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