The structure of Staphylococcus aureus phosphopantetheine adenylyltransferase in complex with 3′-phosphoadenosine 5′-phosphosulfate reveals a new ligand-binding mode

Bacterial phosphopantetheine adenylyltransferase (PPAT) catalyzes the pen­ultimate step in the coenzyme A (CoA) biosynthetic pathway. It catalyzes the reversible transfer of an adenylyl group from ATP to 4′-phosphopantetheine (Ppant) to form dephospho-CoA (dPCoA) and pyrophosphate. Previous structur...

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Detalhes bibliográficos
Main Authors: Lee, Hyung Ho, Yoon, Hye-Jin, Kang, Ji Yong, Park, Ji Hyeon, Kim, Do Jin, Choi, Kwang-Hyun, Lee, Seung-Kyu, Song, Jinsu, Kim, Hie-Joon, Suh, Se Won
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2009
Assuntos:
Structural Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765882/
https://ncbi.nlm.nih.gov/pubmed/19851003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309109036616
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