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HIV-1 Protease Function and Structure Studies with the Simplicial Neighborhood Analysis of Protein Packing (SNAPP) Method

The Simplicial Neighborhood Analysis of Protein Packing (SNAPP) method was used to predict the effect of mutagenesis on the enzymatic activity of the HIV-1 protease (HIVP). SNAPP relies on a four-body statistical scoring function derived from the analysis of spatially nearest neighbor residue compos...

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Detalhes bibliográficos
Main Authors: Zhang, Shuxing, Kaplan, Andrew H., Tropsha, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765824/
https://ncbi.nlm.nih.gov/pubmed/18498108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22094
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