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PHOSPHORYLATED TAU: TOXIC, PROTECTIVE, OR NONE OF THE ABOVE

Identification of phosphorylated tau as the major protein component of neurofibrillary tangles (NFTs) led to the concept that phosphorylated tau was inherently toxic and, as such, intimately involved in Alzheimer’s disease (AD) pathogenesis. While superficially logical, this construct ignores a numb...

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Detalhes bibliográficos
Main Authors: Castellani, Rudy J., Nunomura, Akihiko, Lee, Hyoung-gon, Perry, George, Smith, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765711/
https://ncbi.nlm.nih.gov/pubmed/18688087
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