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Dominant role of CD47–thrombospondin-1 interactions in myeloma-induced fusion of human dendritic cells: implications for bone disease

Lytic bone disease in myeloma is characterized by an increase in multinucleate osteoclasts in close proximity to tumor cells. However, the nature of osteoclast precursors and the mechanisms underlying multinuclearity are less understood. Here we show that culture of myeloma cell lines as well as pri...

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Autors principals: Kukreja, Anjli, Radfar, Soroosh, Sun, Ben-Hua, Insogna, Karl, Dhodapkar, Madhav V.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765677/
https://ncbi.nlm.nih.gov/pubmed/19661269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-03-211920
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