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Low concentrations of amitriptyline inhibit nicotinic receptors in unmyelinated axons of human peripheral nerve
BACKGROUND AND PURPOSE: Amitriptyline is often prescribed as a first-line treatment for neuropathic pain but its precise mode of analgesic action remains uncertain. Amitriptyline is known to inhibit voltage-dependent ion channels and also to act as an antagonist at ligand-gated ion channels, such as...
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Päätekijät: | , , , , , |
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Aineistotyyppi: | Artigo |
Kieli: | Inglês |
Julkaistu: |
Blackwell Publishing Ltd
2009
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Aiheet: | |
Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2765599/ https://ncbi.nlm.nih.gov/pubmed/19694730 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00347.x |
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