Aliskiren reduces body-weight gain, adiposity and plasma leptin during diet-induced obesity

BACKGROUND AND PURPOSE: Overfeeding increases adipose tissue mass and leptin production and up-regulates the renin-angiotensin system in adipose tissue in rodents. Here, we determined the effect of chronic treatment with the renin inhibitor, aliskiren, in a model of diet-induced obesity in mice, on:...

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Bibliographic Details
Main Authors: Stucchi, Paula, Cano, Victoria, Ruiz-Gayo, Mariano, Fernández-Alfonso, María S
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2009
Subjects:
Research Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765596/
https://ncbi.nlm.nih.gov/pubmed/19694726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00355.x
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