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Mammalian pitrilysin: substrate specificity and mitochondrial targeting

The substrate specificity of the mitochondrial metallopeptidase proteinase 1 (MP1) was investigated and its mitochondrial targeting signal identified. The substrate specificity of MP1 was examined with physiological peptides as substrates. Although the enzyme exhibits broad substrate specificity, th...

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Detalhes bibliográficos
Main Authors: Chow, K. Martin, Gakh, O., Payne, I. C., Juliano, Maria Aparecida, Juliano, Luiz, Isaya, G., Hersh, Louis B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765508/
https://ncbi.nlm.nih.gov/pubmed/19196155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi8016125
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