Hypothesis-Driven Candidate Gene Association Studies: Practical Design and Analytical Considerations

Candidate gene association studies (CGAS) are a useful epidemiologic approach to drawing inferences about relations between genes and disease, especially when experimental data support the involvement of specific biochemical pathways. The value of CGAS is apparent when allele frequencies are low, ef...

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Detalhes bibliográficos
Main Authors: Jorgensen, Timothy J., Ruczinski, Ingo, Kessing, Bailey, Smith, Michael W., Shugart, Yin Yao, Alberg, Anthony J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Practice of Epidemiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765367/
https://ncbi.nlm.nih.gov/pubmed/19762372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/aje/kwp242
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