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Hypothesis-Driven Candidate Gene Association Studies: Practical Design and Analytical Considerations
Candidate gene association studies (CGAS) are a useful epidemiologic approach to drawing inferences about relations between genes and disease, especially when experimental data support the involvement of specific biochemical pathways. The value of CGAS is apparent when allele frequencies are low, ef...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2765367/ https://ncbi.nlm.nih.gov/pubmed/19762372 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/aje/kwp242 |
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