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Hypothesis-Driven Candidate Gene Association Studies: Practical Design and Analytical Considerations

Candidate gene association studies (CGAS) are a useful epidemiologic approach to drawing inferences about relations between genes and disease, especially when experimental data support the involvement of specific biochemical pathways. The value of CGAS is apparent when allele frequencies are low, ef...

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Bibliografische gegevens
Hoofdauteurs: Jorgensen, Timothy J., Ruczinski, Ingo, Kessing, Bailey, Smith, Michael W., Shugart, Yin Yao, Alberg, Anthony J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765367/
https://ncbi.nlm.nih.gov/pubmed/19762372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/aje/kwp242
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