Efficacy and MRI of rituximab and methotrexate treatment in a nude rat model of CNS lymphoma

To determine the efficacy of methotrexate and/or rituximab in a CNS lymphoma model and to evaluate MRI modalities for monitoring efficacy, we inoculated female athymic nude rats (rnu/rnu) intracerebrally with human MC116 B-lymphoma cells. Between days 16 and 26, rats were randomized to receive intra...

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Hlavní autoři: Jahnke, Kristoph, Muldoon, Leslie L., Varallyay, Csanad G., Lewin, Seth J., Brown, Robert D., Kraemer, Dale F., Soussain, Carole, Neuwelt, Edward A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Duke University Press 2009
Témata:
Basic and Translational Investigations
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765340/
https://ncbi.nlm.nih.gov/pubmed/19158414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/15228517-2008-119
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