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Efficacy and MRI of rituximab and methotrexate treatment in a nude rat model of CNS lymphoma

To determine the efficacy of methotrexate and/or rituximab in a CNS lymphoma model and to evaluate MRI modalities for monitoring efficacy, we inoculated female athymic nude rats (rnu/rnu) intracerebrally with human MC116 B-lymphoma cells. Between days 16 and 26, rats were randomized to receive intra...

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書誌詳細
主要な著者: Jahnke, Kristoph, Muldoon, Leslie L., Varallyay, Csanad G., Lewin, Seth J., Brown, Robert D., Kraemer, Dale F., Soussain, Carole, Neuwelt, Edward A.
フォーマット: Artigo
言語:Inglês
出版事項: Duke University Press 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765340/
https://ncbi.nlm.nih.gov/pubmed/19158414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/15228517-2008-119
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