Fluvastatin inhibits expression of the chemokine MDC/CCL22 induced by interferon-γ in HaCaT cells, a human keratinocyte cell line

BACKGROUND AND PURPOSE: The macrophage-derived chemokine (MDC/CCL22) is a prototypic Th2-type chemokine intimately involved in Th2-skewed allergic diseases, such as atopic dermatitis and asthma. The statins (3-hydroxy-3-methyl glutaryl coenzyme A reductase inhibitors) have been demonstrated to relie...

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Bibliografiske detaljer
Main Authors: Qi, Xu-Feng, Kim, Dong-Heui, Yoon, Yang-Suk, Li, Jian-Hong, Jin, Dan, Teng, Yung-Chien, Kim, Soo-Ki, Lee, Kyu-Jae
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 2009
Fag:
Research Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765318/
https://ncbi.nlm.nih.gov/pubmed/19594754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00311.x
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